Clinical Effectiveness of Chinese Medicine in Treating Nasopharyngeal Carcinoma Patients with Radioactive Xerostomia:A Systematic Review
10.13359/j.cnki.gzxbtcm.2015.05.015
- VernacularTitle:中医药治疗鼻咽癌患者放射性口腔干燥症临床效果的系统评价
- Author:
Peiyi CHEN
;
Jin WANG
;
Bin LIU
;
Huimin ZHANG
;
Zhenzhen SHAO
;
Yujie LI
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal carcinoma/TCD therapy;
Radioactive xerostomia;
Systematic review
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2015;(5):848-852
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically review the clinical effectiveness of Chinese medicine in treating nasopharyngeal carcinoma patients with radioactive xerostomia. Methods The randomized or semi-randomized controlled trials of the Chinese medicine for nasopharyngeal carcinoam patients with radioactive xerostomia were screened out by online retrieving and manual retrieving of domestic and oversea databases such as Cochrane Library, JBI Library, PubMed, OVID, EMBase, Web of Science, CNKI, Wanfang Database, VIP Database, CBM Database. The data extract and quality assessment were performed by two reviewers independently. Meta-analysis was conducted for the included trials. Results Eight trials were included. The results of Meta-analysis showed that Chinese medicine can effectively delay the progress of oral mucous membrane ulcer in nasopharyngeal carcinoma patients after radiotherapy, and decrease the incidence of grade 3-4 oral mucous membrane ulcer ( Z=4.86, P<0.00001) . Conclusion Chinese medicine has certain effect in treating nasopharyngeal carcinoma patients with radioactive xerostomia.
