High salt intake and bone metabolism
10.3969/j.issn.1000-4718.2016.02.030
- VernacularTitle:高盐摄入与骨代谢
- Author:
Xiaofeng ZHU
;
Ronghua ZHANG
- Publication Type:Journal Article
- Keywords:
Sodium chloride;
Osteoporosis;
Bone metabolism
- From:
Chinese Journal of Pathophysiology
2016;32(2):371-376
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis has become a global public health problem, and dietary interventions may potentially be helpful in preventing this disorder.Salt ( sodium chloride) is one of the most important dietary nutrients.High sodium chloride intake may play an important role in bone metabolism.In this paper, we reviewed the effects of high sodium chlo-ride intake on bone mineral density, bone mineral content and bone biochemical markers, and analyzed the possible causes through currently available literature.Although there are a few inconsistencies results, we conclude a long-term high salt intake can reduce bone density or bone mineral content, change many biochemical markers of bone resorption, which may be caused mainly by increasing urinary calcium excretion and a low-grade metabolic acidosis.However, there are still many unclear aspects need further exploration.
