Therapeutic effect of integrated traditional Chinese and western medicine therapy on reynolds syndrome
10.3760/cma.j.issn.1008-6706.2016.03.023
- VernacularTitle:中西医结合治疗雷诺综合征的疗效观察
- Author:
Yongxing SUN
- Publication Type:Journal Article
- Keywords:
Reynolds syndrome;
Nifedipine;
Aspirin;
Intergrated Chinese Traditional and Western Medicine Theraphy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(3):404-407
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore therapeutic effect of integrated traditional Chinese and western medicine therapy on reynolds syndrome,and to provide effective and reliable operation method for treatment of the disease. Methods 104 cases with reynolds syndrome were randomly divided into observation group (59 cases)and control group (45 cases)by random number table method.The observation group was treated with aspirin,nifedipine combined with traditional Chinese medicine dialectical therapy,the control group was treated with aspirin and nifedipine. The cold water test ,fist test results and hemorheology indexes of the two groups were measured before and after a period of treatment.The therapeutic effects were evaluated after one course.Results After treatment,the fist test, cold water test positive rates of observation group were 32.2%,23.7%,which were lower than 75.6%,57.8% of the control group (χ2 =19.199,12.504,all P <0.05 ).The plasma viscosity (1.25 ±0.11 )mPa · s,erythrocyte aggregation index (2.04 ±0.29),erythrocyte rigidity index (4.20 ±0.58)of the two groups were lower than those before treatment (1.49 ±0.13)mPa·s,(2.27 ±0.30),(4.67 ±0.59),and the deformation index of red blood cell (1.38 ±0.26)was higher than before treatment (1.21 ±0.28)(t =2.704,1.127,9.200,1.687,12.898,5.200, 12.613,5.323,all P <0.05).After treatment,the plasma viscosity,erythrocyte aggregation index and rigidity index of red blood cells were lower than those in the control group,and the deformation index of red blood cells was higher than the control group (t =10.187,3.948,3.195,4.172,all P <0.05).The total effective rate of the observation group was 89.8%(53 /59),which was higher than 71.1%(32 /45 )of the control group,the difference was statistically significant (χ2 =5.991,P <0.05).Drug adverse reaction rate of the observation group was 10.2%(6 /59),that of the control group was 11.1% (5 /45 ),the difference was not statistically significant (χ2 =0.024,P >0.05 ). Conclusion In the treatment of reynolds syndrome,the integrated traditional Chinese and western medicine therapy has better curative effect and low drug adverse reaction rate,with good clinical application value.
