Analysis of Essential Thrombocythemia Combining Myocardial Infarction in 10 Patients
10.3969/j.issn.1000-3614.2016.02.005
- VernacularTitle:原发性血小板增多症合并心肌梗死10例
- Author:
Xu YANG
;
Hui SUN
;
Li DENG
;
Lu HUA
;
Wei ZHANG
;
Xiaoqing HUANG
;
Yun ZHANG
;
Aimin DANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Essential thrombocythemia;
Thrombosis
- From:
Chinese Circulation Journal
2016;31(2):119-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the characteristics, treatment and prognosis in patients with essential thrombocythemia (ET) combining myocardial infarction (MI).
Methods: A total of 10 patients with ET combining MI treated in our hospital from 2003-01 to 2015-07 were retrospectively studied. The basic clinical information with major admission complaints, previous history and peripheral platelet counts were recorded;echocardiograph, coronary angiography (CAG), application of anti-platelet drugs and platelet reductive therapy with the prognosis were recorded in all patients.
Results: There were 6 male and 4 female with a mean age of (55.3 ± 9.7) years, 7 patients with AMI and 3 with old MI. The platelet counts at admission were (500-599) × 109/L in 3 patients, (600-699) × 109/L in 1 patient, (700-799) × 109/L in 3 patients, (800-899) × 109/L in 1 patients, (900-999) × 109/L in 1 patient and more than 1000 × 109/L in 1 patient. Echocardiograph indicated that 5 patient had LVEF≤50%and 5 had LVEF>50%. CAG revealed that there were 9 cases with left anterior descending involved, 2 with circumlfex involved and 5 with right coronary involved. All patients received dual anti-platelet drugs before operation, 4 had hydroxyurea for (20-30) days before operation and no post-operative cardiovascular events occurred;6 patients without hydroxyurea medication and 1 of them was re-hospitalized for angina pectoris and 2 had progressed coronary lesions.
Conclusion: Application of platelet reductive therapy at before and after interventional treatment may improve the prognosis in patients with ET combining MI.
