Content Comparison of Three Ingredients in Notoginseng Radix et Rhizoma and Its Formula Granules
- VernacularTitle:三七药材及其配方颗粒中三成分的含量比较
- Author:
Jiangping ZHENG
;
Zhengde YE
;
Liangyong HUANG
- Publication Type:Journal Article
- Keywords:
Notoginseng Radix et Rhizoma;
Formula granules;
Notoginsenoside R1;
Ginsenoside Rg1;
Ginsenoside Rb1;
Con-tent determination
- From:
China Pharmacist
2016;19(2):374-376
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the contents of notoginsenoside R1 , ginsenoside Rg1 and ginsenoside Rb1 between Notoginseng Radix et Rhizoma and its formula granules. Methods:An HPLC method was used with a SunFire C18 column (250mm × 4. 6 mm, 5μm),the flow rate was 1. 0 ml·min-1, the detection wavelength was set at 203 nm, and the column temperature was at 30 ℃. The mobile phase was acetonitrile( A)-water( B) with gradient elution. An HPLC was used to determine the contents of the three ingredi-ents between Notoginseng Radix et Rhizoma and its formula granules, and compare the differences. Results: The total content of the three ingredients in Notoginseng Radix et Rhizoma and its formula granules was 9. 214% and 8. 646%, respectively. The total content of the three ingredients was equivalent and the daily amount of the major components in the commercial formula granules was equivalent with that in the decoction of Notoginseng Radix et Rhizoma. Conclusion:The production process of the original formula granules is re-liable, and the quality of formula granules of Notoginseng Radix et Rhizoma is stable.
