Determination of Mg, Al and Their Migration of 5-Layer Co-extrusion Bags by ICP-MS
- VernacularTitle:电感耦合等离子体质谱法测定五层共挤输液用袋镁、铝含量及迁移量
- Author:
Xiao YANG
;
Yanping Lü
;
Yan ZHANG
- Publication Type:Journal Article
- Keywords:
ICP-MS;
5-Layer co-extrusion bags;
Mg;
Al;
Migration
- From:
China Pharmacist
2016;19(2):406-407
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a method for the determination of Mg and Al in 5-layer co-extrusion bags and their migration from the bags into infusion by ICP-MS. Methods:The samples were digested by microwave digestion, and the contents of Mg and Al were determined by ICP-MS under certain working conditions. Results:Both Mg and Al had a linear range between 2. 5 and 20. 0 μg ·L-1, and r was 0. 999 6 and 0. 999 7, respectively. The average recovery of Mg was 92. 90% (RSD=3. 01%,n=9),and that of Al was 94. 15% (RSD=4. 11%,n=9). Conclusion:The method is accurate, sensitive and simple, and can be used for the determi-nation of Mg and Al in 5-layer co-extrusion bags and their migration from the bags into infusion.
