Comparison of heparin binding protein and procalcitonin in the evaluation of prognosis of patients with sepsis

VernacularTitle:肝素结合蛋白与降钙素原检测在脓毒症患者预后评估中的作用比较
Author: Xiaojun CHEN ; Xiaohua WANG
Publication Type:Journal Article
Keywords: Sepsis; Procalcitonin; Heparin binding protein; Prognosis
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(2):182-184
CountryChina
Language:Chinese
Abstract: Objective To compare heparin binding protein (HBP)and procalcitonin(PCT)in the evalua-tion of in prognosis of patients with sepsis in ICU.Methods 80 sepsis patients were selected.According to the sever-ity of the disease,they were divided into general sepsis group (n =31),severe sepsis group (n =29)and death group (n =20).The differences of HBP and PCT in three groups were compared.Results Compared with HBP and PCT in the general sepsis group[(3.91 ±0.36)ng/mL,(1.26 ±0.35)ng/mL)],PCT of the severe sepsis group (11.81 ± 0.54)ng/mL was significantly increased(F =2 777.87,P =0.000);HBP and PCT of the death group[(15.28 ± 1.21 )ng/mL,(36.68 ±0.36)ng/mL)]were significantly increased compared with the general sepsis and severe sep-sis groups (F =49 789.02,P =0.000).Conclusion The sensitivity of PCT was significantly higher than HBP in the groups,PCT was better in judging the prognosis of sepsis.