The evaluation by pulmonary wedge angiography of children with pulmonary artery hypertension ;associated with congenital heart disease
10.3969/j.issn.1004-8812.2016.01.005
- VernacularTitle:肺小动脉楔入造影对先天性心脏病患儿肺动脉高压的评估价值
- Author:
Shuna XIAO
;
Xiaoke SHANG
;
Gangcheng ZHANG
;
Yanqing SONG
;
Changdong ZHANG
;
Rong LU
;
Lijun WANG
;
Menghuan YAN
- Publication Type:Journal Article
- Keywords:
Pulmonary artery hypertension;
Pulmonary wedge angiography;
Rote of tapering;
Pulmonary circulation time index
- From:
Chinese Journal of Interventional Cardiology
2016;24(1):18-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study pulmonary wedge angiography ( PWA ) with hemodynamic the evaluation of children with congenital heart disease and pulmonary artery hypertension ( PAH) . Methods Hemodynamic measurement and pulmonary wedge angiography were performed in 50 children with congenital heart disease. Comparison and analysis were made from the data obtained from PWA and catheterization. Results After PWA, the patients were categorized into 3 groups according to the measured hemodynamics parameters:group A [ n=15, patients with normal mean pulmonary artery pressure ( mPAP≤25 mmHg) and normal pulmonary vessel resistance (PVR﹤300 dyne?s?cm5)], group B [n=24, patients with PAH (mPAP﹥25 mmHg) but normal PVR] and group C (n=11, patients with PAH and elevated PVR (PVR≥300 dyne?s?cm5). Rote of tapering (ROT) was significant lower in group C than in group A and B (F=42. 559,P﹤0. 05). Pulmonary circulation time (PCT) was higher in group C than in group A and B (F=6. 037,P﹤0. 05). ROT correlated negatively with PVR (r = -0. 606, P ﹤0. 05). PCT index correlated positively with PVR (r=0. 783,P=0. 01). There was no significant correlation between PCT and mean pulmonary artery hypertension (mPAP). Conclusions PWA may help to make quantitative analysis of the pulmonary vascular status in patients with congenital heart disease.