Progress in genetics of vesicoureteral reflux
10.3760/cma.j.issn.1673-4408.2016.01.003
- VernacularTitle:膀胱输尿管反流相关基因的研究进展
- Author:
Ya ZHANG
;
Qian SHEN
- Publication Type:Journal Article
- Keywords:
Vesicoureteral reflux;
Congenital anomalies of kidney and urinary tract;
Gene;
Ureteric bud;
Metanephric mesenchyme
- From:
International Journal of Pediatrics
2016;43(1):9-13
- CountryChina
- Language:Chinese
-
Abstract:
Vesicoureteral reflux,a most common congenital anomaly of the kidney and urinary tract,is associated with the malformation of ureterovesical junction. It does not cause any specific symptoms or signs un-less it is part of a syndrome or complicated by urinary tract infection. The exact cause is not clear,and genes or environmental factors may result in vesicoureteral reflux. The prevalence of siblings and offspring of reflux pa-tients are higher than normal control groups,so the genetic screening is necessary. This article will review the ge-netics of vesicoureteral reflux and possible interactions.
