Advances in the pathogenesis and treatment of febrile seizures
10.3760/cma.j.issn.1673-4408.2016.01.010
- VernacularTitle:热性惊厥发病机制及干预治疗的研究进展
- Author:
Wenqun ZHANG
;
Zhi HUANG
- Publication Type:Journal Article
- Keywords:
Febrile seizures;
Pathogenesis;
Treatment;
Prevention
- From:
International Journal of Pediatrics
2016;43(1):36-40
- CountryChina
- Language:Chinese
-
Abstract:
Febrile seizures ( FS ) is a common convulsive disorder in infants and young children. It is clinically classified into simple febrile seizures(SFS)and complex febrile seizures(CFS). Although intensively investigated,it remains controversial on the etiology,pathogenesis,treatment,long-term prognosis of FS,even the definition itself is still under debate. This paper briefly reviews recent advances on the underlying mechanisms of FS,including involvement of genetic factors,role of ion channels,and immunologic and neurotransmitter dysreg-ulation. We also gathered some new insights on the treatment and prevention of FS,aiming to improve our under-standing of FS.
