Risk Factor Analysis for Contrast-induced Nephropathy in Patients of Acute Coronary Syndrome With Normal or Slightly Impaired Renal Function After Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2016.01.007
- VernacularTitle:肾功能正常或轻度损害的急性冠状动脉综合征患者经皮冠状动脉介入治疗术后发生对比剂肾病的危险因素分析
- Author:
Jihong FAN
;
Taohong HU
;
Wei HE
;
Zhitao JIN
;
Zheng ZHANG
;
Liping DING
;
Guojie GAO
;
Junke YANG
;
Chengzhu WANG
- Publication Type:Journal Article
- Keywords:
Contrast induced nephropathy;
Acute coronary syndrome;
Angiography;
Risk factor
- From:
Chinese Circulation Journal
2016;31(1):31-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the risk factors for contrast-induced nephropathy (CIN) in patients of acute coronary syndrome (ACS) with normal or slightly impaired renal function after percutaneous coronary intervention (PCI).
Methods: A total of 254 consecutive ACS patients with normal or slightly impaired renal function received PCI in the Second Artillery General Hospital from 2013-06 to 2015-06 were retrospectively studied. All patients had eGRF≥60 ml (min?1.73 m2) and they were divided into 2 groups:CIN group, the patients with serum creatinine increased by 0.5mg/dl (44.2μmol/L) or elevated to 25%higher than the baseline, n=23;Non-CIN group, n=231. The basic condition with laboratory tests, operative indexes were recorded and eGRF value were calculated in all patients.
Results: There were 9%(23/254) patients suffered from CIN after PCI. Multivariate regression analysis indicated that emergent PCI (OR=0.370, 95%CI 0.060-2.297), increased plasma level of NT-proBNP (OR=4.209, 95%CI 1.202-14.742) and without pre-operative aspirin administration (OR=7.950, 95%CI 1.108-57.034) were the clinical risk factors for post-operative CIN occurrence.
Conclusion: Emergent PCI, higher plasma level of NT-proBNP and no pre-operative aspirin administration were the risk factors for CIN occurrence in ACS patients with normal or slightly impaired renal function after PCI.
