Relationship Between the Ratio of Neutrophil/Lymphocyte and In-hospital Major Adverse Cardiac Events in Patients With Acute ST-elevation Myocardial Infarction at the Early Admission
10.3969/j.issn.1000-3614.2016.01.008
- VernacularTitle:急性ST段抬高型心肌梗死患者入院早期中性粒细胞/淋巴细胞比值与院内主要不良心血管事件的相关性
- Author:
Wei HE
;
Jihong FAN
;
Zhitao JIN
;
Liping DING
;
Xin LU
;
Chengzhu WANG
;
Taohong HU
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Major adverse cardiac events;
Neutrophil/lymphocyte
- From:
Chinese Circulation Journal
2016;31(1):36-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between the ratio of neutrophil/lymphocyte (NLR) and in-hospital major adverse cardiac events (MACE) in patients with acute ST-elevation myocardial infarction (STEMI) at early admission.
Methods: A total of 420 acute STEMI patients admitted and received primary PCI in our hospital from 2010-01 to 2014-12 were retrospectively studied. The patients were divided into 2 groups:In-hospital MACE group, n=47 and Normal discharged group, n=373. Uni-and multivariate analyses were conducted to assess whether high NLR is the independent predictor for in-hospital MACE occurrence.
Results: Univariate regression analysis indicated that the occurrence rate of in-hospital MACE in high NLR patients were higher than those in low NLR patients (OR=3.19, 95%CI 1.55-2.65, P=0.012). Multivariate regression analysis showed that high NLR was the independent risk factor for in-hospital MACE occurrence in STEMI patients (OR=3.05, 95%CI 1.59-10.54, P=0.015).
Conclusion: High NLR is the independent risk factor for in-hospital MACE occurrence in STEMI patients at the early admission.