Progress of high density lipoprotein in resisting atherosclerosis
10.3760/cma.j.issn.1009-9158.2016.04.019
- VernacularTitle:高密度脂蛋白抗动脉粥样硬化的研究进展
- Author:
Man ZHU
;
Wei JING
;
Jiancheng TU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Lipoproteins,HDL;
Atherosclerosis;
MicroRNAs
- From:
Chinese Journal of Laboratory Medicine
2016;39(4):315-318
- CountryChina
- Language:Chinese
-
Abstract:
Coronary atherosclerotic heart disease is the leading cause of death in the world of non-infectious diseases.High density lipoprotein ( HDL ) plays an important role in the progression of anti-atherosclerosis.Recent studies have found that HDL can carry microRNA, and the anti-inflammation function of endothelial cell is achieved by the transport of microRNA.The specific functions of different HDL subtypes in the anti-atherosclerosis have been gradually recognized.At the same time, a series of traditional HDL anti-atherosclerotic functions also have been newly discovered, such as reverse cholesterol transport, antioxidant, anti-inflammatory and the protection of vascular endothelium.All of these advances provide a new basis for the clinical application of HDL.
