Clinical Significance of 18F-FDG PET/CT in the Etiological Diagnosis of Postoperative Intestinal Obstruction in Patients with Gastrointestinal Cancer
10.12007/j.issn.0258-4646.2016.05.010
- VernacularTitle:18F-FDG PET/CT显像对胃肠肿瘤术后肠梗阻病因学的诊断价值
- Author:
Xuena LI
;
Na LI
;
Bulin DU
;
Yaming LI
- Publication Type:Journal Article
- Keywords:
intestinal obstruction;
positron emission-tomography;
X-ray computed tomography
- From:
Journal of China Medical University
2016;45(5):422-425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of 18fluorodeoxyglucose positron emission tomography(18F?FDG PET/CT)in the etiological diag?nosis of postoperative intestinal obstruction in patients with gastrointestinal cancer. Methods A total of 51 patients with postoperative intestinal ob?struction undergone 18F?FDG PET/CT were enrolled for the study. The images were interpreted by visual and semi?quantitative analysis(maximum standard uptake value,SUVmax). All the cases were confirmed by pathology and clinical follow?up for more than half a year. The sensitivity,specifici?ty and accuracy of 18F?FDG PET/CT for detecting malignant intestinal obstruction were calculated. Results Of the 51 patients,35 cases were con?firmed for malignant intestinal obstruction,and 16 cases were caused by other benign diseases. 18F?FDG PET/CT imaging was positive in 36 cases, and 33 cases were diagnosed as malignant and recurrent intestinal obstruction. Three cases of PET false?positive were peritonitis adhesion and anasto?motic inflammation. Two cases of PET false negative were peritoneal micrometastasis. The SUVmax of malignant lesions was 8.86±4.82,and the SUVmax of benign lesions was 2.05±1.95. The uptake of FDG was significantly higher in malignant intestinal obstruction than in benign intestinal obstruction (t=7.15,P<0.01). The sensitivity,specificity,and accuracy of 18F?FDG PET/CT diagnosis of malignant lesion were 94.3%,81.3%,and 90.2%, respectively. Conclusion The uptake of 18F?FDG in malignant intestinal obstruction was higher than that in benign intestinal obstruction. 18F?FDG PET/CT have a good diagnostic value for the intestinal obstruction of postoperative gastrointestinal cancer.
