Correlation Analysis between Electrophysiological Features and Mechanical Ventilation and Long-term Outcome in Patients with Guillain-Barré Syndrome
10.12007/j.issn.0258-4646.2016.05.013
- VernacularTitle:吉兰-巴雷综合征患者神经电生理特点及其与机械通气、远期预后的相关性分析
- Author:
Haoyue ZHU
;
Yan LI
;
Juan JIN
;
Shanshan ZHAO
;
Huiling QU
;
Chuansheng ZHAO
- Publication Type:Journal Article
- Keywords:
Guillain-Barré syndrome;
electrophysiology;
mechanical ventilation;
long-term outcome
- From:
Journal of China Medical University
2016;45(5):434-437
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation between the electrophysiological features and mechanical ventilation and long?term outcome in Guil?lain?Barré syndrome(GBS)patients. Methods Electrophysiological and clinical data were retrospectively collected,and compared between venti?lated and not ventilated patients,as well as among each subtype of GBS. Results Totally 38 GBS patients were included in the study,among which 12(32%)were ventilated. The p/d CMAP ratio of the common peroneal nerve was significantly lower in ventilated group compared to not ventilated group(48.7±15.3 vs 80.8±24.0,P=0.005). AIDP was the most common subtype in ventilated patients compared with AMAN and undetermined (46%vs 0%and 9%,P=0.027). The long?term outcome score of AMAN was significantly lower than AIDP(4.3±1.3 vs 2.5±0.9,P=0.028). Conclusion Electrophysiological testing was predictive for mechanical ventilation and long?term outcome:low p/d CMAP ratio of the common pero?neal nerve was helpful for predicting mechanical ventilation,AIDP was prone to develop respiratory failure and had a worse outcome compared to AMAN.
