Correlation Study between hMOF Expression and Prognosis in Patients with Non-small Cell Lung Cancer after Radiotherapy
10.12007/j.issn.0258-4646.2016.04.013
- VernacularTitle:非小细胞肺癌hMOF蛋白表达与放疗预后的关系
- Author:
Xiulin LI
;
Chong HAN
;
Lingrong TANG
;
Yangyang YU
;
Jun DANG
;
Nan LI
;
Guang LI
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
radiotherapy prognosis;
hMOF
- From:
Journal of China Medical University
2016;45(4):340-344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the hMOF protein expression in non?small cell lung cancer and explore the relationship between its expres?sion and radiotherapy prognosis. Methods Immunohistochemical staining was used to detect the hMOF expression in 59 cases of non?small cell lung cancer after radiotherapy. The relationship between hMOF expression with clinicopathological and radiation prognosis was analyzed. Results Among the 59 cases of non?small cell lung cancer tissues,there were 30 cases found to be high expression with hMOF. The rate of positive expression of hMOF in non?small cell lung cancer were 50.85%. Clinical stage and hMOF expression were independent predictors for non?small cell lung can?cer. Conclusion The expression of hMOF had a positive correlation with the radiation prognosis in non?small cell lung cancer,which could be used as a prognostic indicator of radiotherapy.
