Epidemiologic characteristics,risk factors and safety evaluation of traditional Chinese medicine induced liver injury
10.3867/j.issn.1000-3002.2016.04.001
- VernacularTitle:中药肝损伤的流行特点、风险因素及评价
- Author:
Haibo SONG
;
Ling HAN
- Publication Type:Journal Article
- Keywords:
traditional Chinese medicine;
drug-induced liver injury;
risk factors;
safety evaluation
- From:
Chinese Journal of Pharmacology and Toxicology
2016;30(4):291-305
- CountryChina
- Language:Chinese
-
Abstract:
There have been increasing reports on liver injury induced by traditional Chinese medicine (TCM) and natural medicine in recent years. The risk of liver injury induced by TCMs has attracted more attention at home and abroad. In this paper,epidemiologic characteristics,risk factors,clinical features of TCMs induced liver injury were discussed. The myth about research and safety evaluation of TCMs induced liver injury was analyzed. Based on the property of TCMs and characteristics of their clinical use,this paper proposed the priorities of basic and clinical safety evaluation of TCMs induced liver toxicity. It is hoped that this study may provide reference for scientific evaluation of liver toxicity of TCMs.
