Research progress on Sprouty protein in tumor
10.3969/j.issn.1000-8179.2016.08.162
- VernacularTitle:Sprouty在肿瘤中的研究进展
- Author:
Ke WANG
;
Guoxing WANG
- Publication Type:Journal Article
- Keywords:
Sprouty protein;
signaling pathway;
tumor
- From:
Chinese Journal of Clinical Oncology
2016;43(8):358-360
- CountryChina
- Language:Chinese
-
Abstract:
The Sprouty protein can inhibit cel proliferation and induce apoptosis by specific interventions in the signaling pathways of tumor cells, such as receptor tyrosine kinase signaling pathway. The Sprouty protein, which is often associated with abnormal cell proliferation and transformation, is down-regulated in many tumors, stimulating the initiation and progression of tumors. The Sprouty protein exhibits potential for developing effective treatment against cancer. This paper reviews research progress on Sprouty protein in tumor.