The effects of diagnostic and treatment operation of the urinary diseases on serum prostate specific antigen levels
10.3969/j.issn.1673-4130.2016.08.011
- VernacularTitle:泌尿系统疾病诊断和治疗操作对血清前列腺特异抗原检测的影响
- Author:
Huizhen LI
;
Wenhui YU
;
Zhipeng WEN
;
Qinong MO
;
Linli SONG
;
Chunhua LI
;
Dan ZHOU
;
Rui YUAN
;
Shenghua LUO
- Publication Type:Journal Article
- Keywords:
urinary system;
diagnosis;
treatment;
prostate specific antigen
- From:International Journal of Laboratory Medicine
2016;37(8):1041-1043
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of diagnostic and treatment manipulation of the urinary diseases on serum prostate specific antigen(PSA) levels .Methods 80 male patients were recruited from urology surgery department of Shenzhen Tranditional Chinese Medicine (TCM ) Hospital ,Which included 13 cases with digital rectal examination (DRE) ,10 cases with catheterization , 12 cases with rigid cystoscopy ,17 cases with prostate biopsy ,28 cases with transurethral resection of the prostate (TURP) .Blood samples of 80 patients were collected before diagnostic and treatment manipulation of the urinary diseases and 24 h ,3 d ,7 d ,14 d af‐ter that ,respectively .Then ,serum total prostate antigen(TPSA) and free prostate antigen (FPSA) was measured .Results There was no effects of DRE on serum TPSA and FPSA levels(P>0 .05) .On the contrary ,serum TPSA and FPSA levels increased sig‐nificantly in patients with catheterization and cystoscopy(P<0 .05) ,and the duration was longer(7-14 d) .Serum TPSA and FPSA levels increased significantly(P<0 .05)in patients with TURP and biopsy at the 24th hour after manipulation and it began to de‐crease on the third day .Also ,the serum TPSA and FPSA levels decreased to baseline after 14 days .Conclusion There′re no effects of DRE on serum TPSA and FPSA levels .However ,serum TPSA and FPSA levels increase differently in patients with catheteriza‐tion ,cystoscopy ,biopsy and TURP ,but the durations were different ,too .
