Effect of Shenju Lotion Agaisnt Trichomonas in Vagina In Vitro
10.3870/j.issn.1004-0781.2016.05.006
- VernacularTitle:参菊洗剂体外抗阴道毛滴虫作用
- Author:
Guangqiu ZHANG
- Publication Type:Journal Article
- Keywords:
ShenJu lotion;
Trichomonas,vagina;
Experiment,in vitro
- From:
Herald of Medicine
2016;35(5):458-460
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the in vitro effect of ShenJu lotion agaisnt Trichomonas vaginalis in order to provide clues for its clinical application. Methods ShenJu lotion was formulated into different concentrations(400.00,200. 00,100.00,50.00,25.00,12.50,6.25 mg·mL-1 )with liver extracts.The morphology and movement of Trichomonas vaginalis treated with different concentrations of ShenJu lotion in vitro for 2,4,6,8,12,or 24 h were observed and the mortality was calculated.The effects against Trichomonas vaginalis were compared between Jieeryin lotion and ShenJu lotion at the same concentrations. Results ShenJu lotion could significantly inhibit and kill clinical isolates of Trichomonas vaginalis in vitro and the lowest effective concentration was 50.00 mg·mL-1 .There was no significant difference in the mortality between ShenJu lotion and Jieeryin lotion(P>0.05). Conclusion ShenJu lotion has obvious effects against Trichomonas vaginalis.