Clinical Features and Associated Abnormalities in Children and Adolescents With Corpus Callosal Anomalies.
10.5535/arm.2014.38.1.138
- Author:
Young Uhk KIM
1
;
Eun Sook PARK
;
Soojin JUNG
;
Miri SUH
;
Hyo Seon CHOI
;
Dong Wook RHA
Author Information
1. Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea. medicus@yuhs.ac
- Publication Type:Case Report
- Keywords:
Callosal agenesis;
Gross motor function
- MeSH:
Adolescent*;
Brain;
Central Nervous System;
Cerebral Palsy;
Child*;
Classification;
Humans;
Magnetic Resonance Imaging;
Retrospective Studies;
Seizures
- From:Annals of Rehabilitation Medicine
2014;38(1):138-143
- CountryRepublic of Korea
- Language:English
-
Abstract:
Callosal anomalies are frequently associated with other central nervous system (CNS) and/or somatic anomalies. We retrospectively analyzed the clinical features of corpus callosal agenesis/hypoplasia accompanying other CNS and/or somatic anomalies. We reviewed the imaging and clinical information of patients who underwent brain magnetic resonance imaging in our hospital, between 2005 and 2012. Callosal anomalies were isolated in 13 patients, accompanied by other CNS anomalies in 10 patients, associated with only non-CNS somatic anomalies in four patients, and with both CNS and non-CNS abnormalities in four patients. Out of 31 patients, four developed normally, without impairments in motor or cognitive functions. Five of nine patients with cerebral palsy were accompanied by other CNS and/or somatic anomalies, and showed worse Gross Motor Function Classification System scores, compared with the other four patients with isolated callosal anomaly. In addition, patients with other CNS anomalies also had a higher seizure risk.
