Effect and function analysis of sulfentanyl on tongue cancer in patients with postoperative analgesia
10.3969/j.issn.1005-1678.2016.04.27
- VernacularTitle:舒芬太尼在舌癌患者术后镇痛中的效果及作用分析
- Author:
Liu LUO
;
Dong HUANG
- Publication Type:Journal Article
- Keywords:
sulfentanyl;
tongue cancer;
self-controlled intravenous analgesia
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(4):92-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect and function analysis by sulfentanyl in patients with tongue cancer postoperative analgesia.Methods A total of 74 patients with radical resection of tongue cancer in department of anesthesiology with general anesthesia from our hospital were collected, patients or their families signed consent, according to postoperative self-controlled intravenous analgesia drugs divided into experimental group and control group with 37 cases in each group.Patients in control group were treated by fentanyl self-controlled intravenous analgesia;patients in experimental group were treated by sulfentanyl self-controlled intravenous analgesia, determination of the analgesic effect, sedative effect and the changed of vital signs postoperative 2, 4, 8, 12, 24, 48 h,at the same time recorded complications.Results After operation, at different time points analgesic effect and sedative effect were changed in the two groups, the VAS scored of the experimental group was lower than the control group postoperative 2, 4, 8, 12, 24, 48 h time points, the Ramsay Sedation scored of the experimental group was lower than the control group postoperative 2 h, 4 h, 8 h, 12 h time points ( P <0.05 ); the changed of vital signs and adverse reactions between the two groups had no difference within 48 hours ( P >0.05 ) . Conclusion Sulfentanyl in the treatment of patients with radical resection of tongue cancer the analgesic effect and sedative effect are better than fentanyl, has no effect on the vital signs, and the role is security and exact.
