Effect of glucocorticoid combined with Qingkailing injection on serum IL-10 and TNF-αlevels in lobar pneumonia patients
10.3969/j.issn.1005-1678.2016.04.48
- VernacularTitle:清开灵注射液联合糖皮质激素对大叶性肺炎患者血清IL－10及TNF－α水平的影响
- Author:
Jianbo WU
;
Zhimin HE
- Publication Type:Journal Article
- Keywords:
glucocorticoid;
Qingkailing injection;
lobar pneumonia;
IL-10;
TNF-alpha
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(4):152-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigation effect of glucocorticoid combined with Qingkailing injection on lobar pneumonia IL-10 and serum TNF-levels.Methods 120 cases of lobar pneumonia in children were selected respiratory department fromasin our hospital in December 2012 to December 2014 as the object of study, were divided into control group and observation group, control group were treated with dexamethasone sodium phosphate injection,the observation group in the control group based on the combined with Qingkailing injection, serum IL-10, TNF-a level and curative effect were compared between the two groups pre-and post-treatment in patients.Results The total effective rate of the observation group was 86.67%, higher than that of the control group, the total effective rate was 70%(P <0.05).Before treatment, the two groups of patients with TNF-αand IL-10 were not statistically significant difference.After treatment, the two groups of patients with TNF-αand IL-10 were decreased, and lower than the control group (P<0.05) .Conclusion Glucocorticoid combined with Qingkailing injection can reduce serum IL-10, TNF-alpha level in lobar pneumonia,has a definite effect.
