Compatible Stability of Carbohydrate-Electrolyte Injection and Commonly Used Vitamin-Electrolyte Injections
10.3870/j.issn.1004-0781.2016.05.025
- VernacularTitle:混合糖电解质注射液与常用维生素电解质配伍的稳定性
- Author:
Lan XU
;
Jizhi CHEN
;
Xiaoxuan TAO
;
Chuanhua FENG
;
Gang LI
;
Jing ZHANG
- Publication Type:Journal Article
- Keywords:
Carbohydrate-electrolyte injection;
Sodium acetate;
Chromatography,high performance liquid;
Stability,compatibility
- From:
Herald of Medicine
2016;35(5):526-529
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the compatible stability of the carbohydrate-electrolyte injection and commonly used vitamin-electrolyte injections. Methods By simulating clinical use of medicines,the carbohydrate-electrolyte injection and various vitamin-electrolyte injections were mixed respectively.The content of sodium acetate was measured by HPLC,and changes in appearance,pH value and insoluble particles of the injections were observed. Results At room temperature,the compatibility solutions showed no significant changes in appearance,pH value,the number of insoluble particles and the content of sodium acetate within 8 h. Conclusion The carbohydrate-electrolyte injection is compatible with commonly used vitamin-electrolyte injections,and the admixtures are stable within 8 h at room temperature.
