Proficiency evaluation of laboratories for the detection of esterase-3 in the kidneys of laboratory mice
10.3969/j.issn.1005-4847.2016.02.018
- VernacularTitle:实验小鼠肾匀浆中酯酶-3的实验室测定能力验证结果评价
- Author:
Jie WEI
;
Hong WANG
;
Wei GONG
;
Zhengming HE
;
Bingfei YUE
- Publication Type:Journal Article
- Keywords:
Capacity evaluation;
Quality control;
Laboratory animal;
Esterase-3
- From:
Acta Laboratorium Animalis Scientia Sinica
2016;24(2):204-207
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the detection capacity of esterase-3 ( Es-3) in the laboratory animals monito-ring laboratories in China, and to improve the quality management of laboratories.Methods We prepared the test sam-ples according to the criteria of China National Accreditation Service for Conformity Assessment(CNAS), all the samples were certificated by homogeneity test and stability test.Then, samples with random numbers and standard operation instruc-tion were distributed to the participant laboratories.The laboratories should submit their reports before the deadline expires. When the results are the same as the standard results, the laboratories will receive excellent remark; when the results are the same as the standard results except the hybridization type, the laboratories will receive satisfactory remark;otherwise, it will receive unsatisfactory remark.If a laboratory did not submit report, the laboratory will also receive unsatisfactory re-mark.Results Ten laboratories participated in the program, and no laboratory received excellent remark.Nine laboratories (90.0%of enrolled laboratories) had satisfactory results, while one laboratory (10.0%of enrolled laboratories) had un-satisfactory results.Conclusions The nationwide overall detection level of laboratories in Es-3 is relatively high.Howev-er, some details should be noticed and several laboratories should improve their detecting ability.
