CT and pathological analysis of peripheral primitive neuroectodermal tumors in abdomen-pelvis region
10.3969/j.issn.1002-1671.2016.04.014
- VernacularTitle:腹盆部外周型原始神经外胚层瘤的CT 诊断与病理分析
- Author:
Haiyang WANG
;
Yamin WAN
;
Yonggao ZHANG
;
Jianbo GAO
;
Liang GE
- Publication Type:Journal Article
- Keywords:
peripheral primitive neuroectrodermal tumors;
computed tomography;
immunohistochemistry
- From:
Journal of Practical Radiology
2016;32(4):547-550
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlations of clinical characteristics,CT and pathology features of peripheral primitive neuroectrodermal tumors (pPNET)in abdomen-pelvis region,and to improve the understanding of the disease.Methods The clinical information,CT and pathological features of 23 confirmed pPNET patients in abdomen-pelvis region were analyzed retrospectively.Results (1)All patients had preoperative clinical and imaging data integrallty.(2)23 cases showed soft tissue masses with fuzzy boundary and the average diameter were 10.72 cm.Among all,9 cases showed with varying degrees of sac necrosis,while 2 cases showed with platelet hemorrhage and 4 cases with speckled calcifications.Most showed slight-to-moderate heterogeneous enhancement and the necrosis and cystic are-as showed more obvious.12 cases showed with different degree of recurrence,invasion or distant metastasis.5 cases combined with tumor emboli and 4 cases with tumor feeding vessels.(3)Immunohistochemical examination showed CD99 expressed in 1 9 patients, CD56 in 11,vimentin(Vim)in 12,synaptophysin(Syn)in 11,neuron specific enolase(NSE)in 4,FLI-1 in 4 and epithelial membrane antigen (EMA)in 4 patients.Conclusion pPNET is common among young patients with a high degree of malignancy.CT features include large mass with invasive growth,commonly combined heterogenous density,necrosis and cystic changes.Persistent enhancement is observed during nephrographic phase.
