Optimization of Ethanol Extraction Technology forDingtongning Granule by Orthogonal Design
10.3969/j.issn.1005-5304.2016.05.021
- VernacularTitle:正交试验法优选定痛宁颗粒的乙醇提取工艺
- Author:
Lei ZHANG
;
Anwei DING
- Publication Type:Journal Article
- Keywords:
Dingtongning Granule;
ethanol extraction technology;
tanshinoneⅡA;
orthogonal design
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(5):83-86
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize ethanol extraction technologyDingtongning Granule.Methods With yield of extract and content of tanshinoneⅡA as comprehensive evaluation indexes, the concentration of ethanol, the amount of ethanol, soaking time, extraction time and extraction times were selected as observing factors. Orthogonal design test L18(37) was used to optimize ethanol extraction technology ofDingtongning Granule.Results Optimum extraction conditions were as follows: soaking medicine for 0 hour; 2 times with 6 times of the amount of 80% ethanolre; flux extracted 3 hours each time.Conclusion This optimal extraction technology is stable and reliable, which can provide basis for industrial production ofDingtongning Granule.
