Application and progress in endothelial progenitor cells in hypertension

VernacularTitle:内皮祖细胞与高血压病的应用研究进展
Author: Wenhua LI ; Qunhui ZHANG ; Hao RONG ; Peng CAI ; Dongya YUAN
Publication Type:Journal Article
From: Chinese Journal of Tissue Engineering Research 2016;20(15):2273-2280
CountryChina
Language:Chinese
Abstract: BACKGROUND:Structural and functional changes of endothelial cels are the common pathological basis of cardiovascular disease. Severe structural and functional damage of endothelial cels are found in patients with hypertension or coronary heart diseases.
OBJECTIVE:To explore a new treatment method for hypertension from the perspective of vascular endothelial progenitor cels.
METHODS: PubMed and Wanfang databases were retrieved using the keywords “hypertension, EPCs” and approximately relevant 200 English and 100 Chinese literatures were obtained. Forty-nine eligible literatures were screened finaly.
RESULTS AND CONCLUSION:Endothelial progenitor cels have strong differentiation and proliferation capacities. This review may provide a new insight into potential sources of cels for diagnosis and treatment of hypertension.