Genetics of sporadic cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2016.01.014
- VernacularTitle:散发性脑小血管病的遗传学
- Author:
Yangyang WANG
;
Sainan CHEN
;
Yuying SUN
;
Yuming XU
;
Jun WU
- Publication Type:Journal Article
- Keywords:
Cerebral Smal Vessel Diseases;
Stroke,Lacunar;
Leukoencephalopathies;
Cerebral Hemorrhage;
Genetic Predisposition to Disease;
Polymorphism,Single Nucleotide;
Genome-Wide Association S tudy
- From:
International Journal of Cerebrovascular Diseases
2016;24(1):80-83
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral smal vessel disease (CSVD) can be divided into sporadic and hereditary CSVD. The exact pathogenesis of sporadic CSVD is unknow n. Genetic factors may also play an important role, except for environmental and vascular risk factors. As a complicated disease, sporadic CSVD has the characteristics of multigenetic susceptibility. Therefore, investigating the related genetic factors may contribute to understanding the pathogenesis of sporadic CSVD. This article review s the advances in research on the genetics of sporadic CSVD.
