Animal selection for thin endometrium model and improved technique for its establishment
10.3969/j.issn.1005-4847.2016.02.021
- VernacularTitle:薄型子宫内膜模型的动物选择及其造模方法改进
- Author:
Chunyan XU
;
Yang SONG
;
Kunyin LI
;
Yongge GUAN
;
Weizhi FAN
- Publication Type:Journal Article
- Keywords:
Thin endometrium;
Animal models;
Establishment method
- From:
Acta Laboratorium Animalis Scientia Sinica
2016;24(2):217-220
- CountryChina
- Language:Chinese
-
Abstract:
Thin endometrium is an important factor influencing the in vitro fertilization and embryo transfer, and there is a lack of effective therapy in the treatment of thin endometrium.The aim of this study was to explore a stable animal model of effective thin endometrium, and to promote the research on thin endometrium pathogenesis and provide experimen-tal basis of treatment.To analyze a variety of establishments of endometrial damage animal model reported in the domestic and foreign literatures,it is concluded that perfusing 95% ethanol into uterine cavities of rats can establish a rat model of thin endometrium,and put forward some experience and methods for its improvement.