The analysis study based on 973 azoospermia patients′testicular volume,reproductive hormones and sperm cytological
10.3969/j.issn.1673-4130.2016.07.022
- VernacularTitle:973例无精子者睾丸体积、生殖激素与精液细胞学分析
- Author:
Changwei YUAN
;
Xingwu CAO
- Publication Type:Journal Article
- Keywords:
non-obstructive azoospermia;
obstructive azoospermia;
reproductive hormones;
testicular volume;
spermat-ogenic cell
- From:
International Journal of Laboratory Medicine
2016;37(7):925-927
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the testicular volume and reproductive hormones level with sperm cytological detection results in azoospermic patients .Methods Based on the WHO male infertility etiology diagnosis classification criteria ,973 azoospermic patients were divided into the obstructive azoospermia (OA ) and non‐obstructive azoospermia (NOA ) . Then NOA was divided into the existing spermatogenic cells type group and non‐existing spermatogenic cells type group according to the sperm spermatogenic cell detection results .The testicular volume and reproductive hormones levels were statistically analyzed and compared among various groups .Results In 973 azoospermia patients ,235 cases were OA (24 .15% ) and 738 cases were NOA (75 .85% ) .There were 410 cases (55 .56% ) of existing spermatogenic cells type and 328 cases(44 .44% ) of non‐existing spermato‐genic cells type .The testicular volume in the existing spermatogenic cells type group and non‐existing spermatogenic cells of NOA was clearly reduced ,the T and T/LH were lower ,while the LH and FSH levels were significantly increased ,the difference between the OA group and the NOA group had statistical difference (P<0 .001) ,but PRL had no statistical difference between them (P<0 .05) .The testicular volume of existing spermatogenic cells type was smaller than non‐existing spermatogenic cells type ( P<0 .001) .The LH and FSH levels were higher than those of existing spermatogenic cells type (P<0 .01 ,P<0 .05);T ,T/LH and PRL levels had no statistical difference (P>0 .05) .Conclusion The testicular volume and reproductive hormones level are closely related with the detection quantity of sperm cells and the detection of T /LH is helpful for understanding the relation between the function of leydig cells and basement membrane change .
