Research Progress on Relationship Between Gastroesophageal Flap Valve and Gastroesophageal Reflux Disease
10.3969/j.issn.1009-6604.2016.04.020
- VernacularTitle:胃食管阀瓣与胃食管反流病关系的研究进展
- Author:
Ji KE
;
Jixiang WU
;
Jianye LI
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux disease;
Gastroesophageal flap valve;
Erosive esophagitis
- From:Chinese Journal of Minimally Invasive Surgery
2016;16(4):362-364
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] The mechanisms of gastroesophageal reflux disease ( GERD) include abnormal antireflux function and esophageal mucosa attacked by regurgitation .Gastroesophageal flap valve ( GEFV) located in the gastroesophageal junction is one mechanism of the antireflux barrier .An increased GEFV grade is associated with an increased incidence of erosive esophagitis and Barrett ’ s epithelium.With abnormal esophageal acid exposure and prevalence of a mechanically defective sphincter , patients usually have severe symptoms and lower efficiency of medication .Therefore , GEFV is valued in the diagnosis and treatment of GERD .This review summarized the relationship between GEFV and GERD .
