Prevalence and influence factors of retinopathy in premature infants and term infants less than gestational age infants
10.3760/cma.j.issn.1008-6706.2016.08.034
- VernacularTitle:早产儿及低体质量儿视网膜疾病的发病率及影响因素
- Author:
Xueyin ZHANG
- Publication Type:Journal Article
- Keywords:
Retinal disease;
High risk factors;
Premature infants
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(8):1244-1247
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prevalence and risk factors of retinopathy ( ROP) in premature infants and full term infants.Methods 563 premature infants and full term infants in Weihai Hospital Affiliated to Medical College of Qingdao University from January 2014 to January 2015 were selected,and the clinical data were retrospec-tively analyzed.Results 61 children with ROP,the incidence rate of ROP was 10.83%.Men incidence rate of ROP (10.68%) and female incidence of ROP (11.02%) showed no significant difference (χ2 =1.045,P>0.05).The gestational age >35 weeks, 31 -34 weeks,≤30 weeks neonatal ROP incidence rates were 1.53%, 15.04%, 35.71%,the difference between groups was statistically significant(χ2 =11.455,P<0.05).And with the smaller the gestational age,ROP incidence was higher.Birth weight >2 000g,1 500g-2 000g,<1 500g neonatal ROP incidence rates were 5.83%,13.46%,32.61%,the difference between groups was statistically significant (χ2 =10.733,P<0.05),and with the smaller birth weight,ROP incidence was higher.There was a close correlation between mechani-cal ventilation,apnea and ROP (χ2 =11.455,9.765,all P<0.05);the rate of cesarean section,multiple births, blood transfusion,premature rupture of membranes was not significantly correlated with the rate of ROP (χ2 =0.732, 1.175,1.542,1.782,all P>0.05).Multivariate unconditional logistic regression analysis,the independent risk fac-tors of retinal diseases for preterm and full-term children small for gestational age children were birth gestational age,birth weight,mechanical ventilation,apnea.Conclusion The age of birth,birth weight,mechanical ventilation and apnea are the risk factors of ROP.It should be attached great importance to the clinical treatment to prevent the development of the disease and improve the prognosis of patients.
