Investigation on reference ranges of peripheral white blood cells and five classification parameters among 13 442 children
10.3969/j.issn.1673-4130.2016.07.008
- VernacularTitle:13442例儿童末梢血白细胞及五分类参数参考范围调查
- Author:
Yukai HUANG
;
Rui LIU
;
Xiaoqiong GU
;
Xiaoyun LIANG
;
Lanlan ZENG
;
Fei LIU
;
Qihua LIANG
- Publication Type:Journal Article
- Keywords:
healthy child;
white blood cell;
reference interval
- From:
International Journal of Laboratory Medicine
2016;37(7):886-889
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the reference ranges of peripheral white blood cells (WBC) and five classification parame‐ters among 13 442 apparently healthy children to provide reference for clinical diagnosis .Methods A total of 13 442 apparently healthy children aged from 1 month old to 5 years undergoing the health physical examination in the healthcare department of the Guangzhou Municipal Women and Children Medical Center were chosen according to the healthy children screening standard and the exclusion standard of hematological diseases ,infection diseases and drug administration history .The WBC analysis and its parame‐ters detection were performed by using the Sysmex XS‐800i automatic blood cell analyzer .Results WBC and its five classification parameters were not accorded with the normally distribution .By the Mann‐whitney test ,no statistically significant differences in WBC ,BASO# and NEU # were detected between different genders of children (P> 0 .05) ,while the differences in LYM # , MONO# and EOS# had statistical significance(P<0 .001) ,in which the LYM # level in females was significantly higher than that in males ,while the MONO# and EOS# levels in females were lower than those in males ;By the Kruskal‐Wallis test ,WBC and five classification parameters had statistically significant differences among different age groups (P<0 .001) .The parameters of WBC ,LYM # ,MONO# and EOS# were decreased with age increase ,while NEU # was constantly increased with age increase and BASO# was decreased with age increase before 4 years old .Conclusion All factors such as gender ,age should be The inde‐pendent reference rangesl of WBC parameters among children aged from 1 month old to 7 years old should be formulated on the ba‐sis of fully considering the factors such as gender ,age .
