The efficacy of 125I radio active particle implantation in the treatment of maxillofacial malignancy of 43 cases
10.3969/j.issn.1001-3733.2016.02.014
- VernacularTitle:125I放射粒子植入治疗颌面部性恶性肿瘤43例疗效分析
- Author:
Xiu YAO
;
Ling GU
;
Ying LIU
;
Shuangshuang LI
;
Dong WANG
;
Lu YANG
;
Lihong XU
;
Chongjian FU
- Publication Type:Journal Article
- Keywords:
Maxillofacial malignant tumor;
125I radioactive particles;
Clinical effect;
Survival rate
- From:
Journal of Practical Stomatology
2016;32(2):220-224
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of 125I radioactive particle implantation in the treatment of maxillofacial malignancy. Methods:43 patients with maxillofacial malignancy were treated with 125I radioactive particle implantation.The procedure was carried out according to the treatment planning system(TPS),with the particles spaced uniformly at 1 cm intervals and with the activity of 0.7 m Ciby 41 particles per case on a verage.All patients were followed up for 6-60 months.Results:The whole treatment procedurewas successful,and no particle displaced.The follow-up rate was 93.02% and treatment effective rate(CR+PR) was 90.70%.Norecur-rence was foundinall target areas.The mortality due to tumor was 9.30%and total survival rate was 74.43%.The cumulative survival rate of the patients in 0.5,1,2,3 and 5 years was 93.0%,85.7%,79.3,69.8% and 56.9% respectively.Survival periodon aver-age was 36.06-50.04 months,with the median of 43.05 months.The longest tumor-free survival period was 60 months.Radiation in-jury rate was 20.93% and only level 1 radiation injury was observedinall the cases.Facial nerve dys function was found in 2 cases and recovered after treatment.Conclusion:Treatment of maxillofacial malignancy by implantation of 125I particles is convenient and mini-mally invasive.The treatment canincrease survival rate of the patients and guaran tee the oropharynxes' function.
