The gene type of Candida albicans in the oral cavity of Uygur children aged 3 -5 years with high caries
10.3969/j.issn.1001-3733.2016.02.021
- VernacularTitle:维吾尔族高龋儿童口腔中白色念珠菌基因分型研究
- Author:
Nan WU
;
Haitao DAI
;
Jiang XU
- Publication Type:Journal Article
- Keywords:
Candida albicans(CA);
Genotype;
25SrDNA-PCR
- From:
Journal of Practical Stomatology
2016;32(2):252-255
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the oral Candida albicans(CA)distribution in Uyghur children and to explore the gene type of CA in the children with high caries.Methods:The oral CA of 144 Uyghur children aged 3 -5 years was detected and identified by CHROMagar Candida medium culture,biochemical identification and PCR respectively.Gene type in 25 samples of high caries was de-tected by PCR25r-genotyping.Results:CA was found in 35(24.3%)of the children,and 25 of them with high caries.The gene type of CA was divided into type A,B and C,A was the major(72.0%).Conclusion:Oral Candida albicans may be related to childhood caries of Uygur population.Candida albicans with genotype A may be more cariogenic in Uygur children.