P2X3 receptor expression in lingual nerve fibres of patients with burning mouth syndrome
- VernacularTitle:P2X3受体在灼口综合征患者舌组织神经纤维中的表达
- Author:
Qimei ZHANG
;
Minhai NIE
;
Yi HE
;
Cong ZHOU
- Publication Type:Journal Article
- Keywords:
P2X3;
Burning mouth syndrome(BMS);
Chronic pain
- From:
Journal of Practical Stomatology
2016;32(2):277-279
- CountryChina
- Language:Chinese
-
Abstract:
Patients with burning mouth syndrom(BMS,n =12)and patients with wisdom tooth removal(controls,n =9)were included. Immunohistochemistry and image analysis were used to quantify P2X3 receptor expression in lingual nerve fibres.A pain history and score were recorded on a visual analogue scale(VAS)prior to obtaining a lingual biopsy.The value of P2X3 receptor positive fibres in BMS and control subjects was 0.56 ±0.29 and 0.15 ±0.06 respectively(P <0.001).There was no significant correlation between P2X3 and VAS scores(R2 =0.012).Increased P2X3 may play a role in BMS but not correlated with the VAS score.
