The impact of repeated app1ication of contrast media on rena1 function within a short period of time ;in different occasions
10.3969/j.issn.1004-8812.2016.03.006
- VernacularTitle:短时间内经不同途径重复应用对比剂对患者肾功能的影响
- Author:
Yao ZHANG
;
Xiang TIAN
;
Qi ZHANG
;
Libo ZHEN
;
Wei GENG
;
Qianmei LIU
;
Ying YANG
;
Da SONG
- Publication Type:Journal Article
- Keywords:
Contrast-induced nephropathy;
Coronary angiography;
Percutaneous coronary intervention
- From:
Chinese Journal of Interventional Cardiology
2016;24(3):149-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the impact of repeated contrast media exposure on renal function in patients who received coronary angiography ( CAG) or percutaneous coronary intervention ( PCI) within 1 week after CTA of coronary ateries. Methods A total of 258 patients who received CAG or PCI after coronary CTA were divided into the study group ( n=132, patients had CAG/PCI within 1 week after CTA) and the control group ( n=126, patients had CAG/PCI 1-2 weeks after CTA). Serum creatinine, cystatin C and estimated GFR were tested before and on day 1, 2 and 3 after procedures. The occurance of contrast-induced nephropathy ( CIN ) was recorded. Resu1ts The baseline clinical characteristics of the patients between the two groups had no significant difference. Preoperative and postoperative serum creatinine, cystatin C and eGFR values on day 1, 2 and 3 had no significant difference between the two groups (all P﹥0. 05). There was no significant difference in the incidence of CIN between two groups (5. 3% in the study group vs. 4. 8% in the control group, P﹥0. 05 ) . Conc1usions It is safe and feasible for patients with eGFR≥60 ml/( min?1. 73 m2 ) to undergo CAG or PCI within 1 week after coronary CTA.