Diagnostic and therapeutic value of open food challenge in children of cow′s milk protein allergy
10.3969/j.issn.1000-484X.2016.04.026
- VernacularTitle:开放性食物激发试验在牛奶蛋白过敏诊治中的应用价值
- Author:
Zhuang PI
;
Xintong Lü
;
Lan WU
;
Zhaoxia WANG
- Publication Type:Journal Article
- Keywords:
Cow′s milk protein allergy;
Open food challenge;
Diagnosis and treatment
- From:
Chinese Journal of Immunology
2016;32(4):567-569
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the diagnostic and therapeutic value of open food challenge in children with cow ′s milk protein allergy.Methods:It is a retrospective analysis of 55 children with suspected cow′s milk protein allergy ( CMPA ) who attended the clinic of the pediatric gastroenterology department ,the First Hospital of Jilin University from March 2014 to March 2015.These children were fed by a mino acid based formulae ( AAF) for 2-4 weeks and then open food challenge ( OFC) test was performed.Those children who tested positive , were diagnosed as having CMPA.They were then fed with AAF for further 3 months and OFC was performed again.Then discusse the diagnostic and therapeutic value of open food challenge in children with cow ′s milk protein allergy.Results:Out of 55 CMPA suspected children ,52 tested positive with OFC yielding a positive rate of 94.55%.These 52 children were fed with AAF for further 3 months and then tested with OFC ,9 children tested positive yielding a positive rate of 17.30%.These 9 children were again fed with AAF for 3 months and then tested with OFC.This time 2 children tested positive yielding a positive rate of 3.85%.Con-clusion:Open food challenge teats are of great significance in the diagnosis of CMPA ,and evaluation of tolerance to cow′s milk protein ( CMP).
