Isolation and Identification of Triterpenoids from Acanthopanax Sessiliflorus Fruits
- VernacularTitle:短梗五加果中的三萜类化合物分离与鉴定
- Author:
Yonghai MENG
;
Xinwei WANG
;
Qiong WU
;
Gaosong WU
;
Hai JIANG
;
Chunmei ZHAI
;
Chunjuan YANG
;
Yang SONG
;
Zhibin WANG
- Publication Type:Journal Article
- Keywords:
Acanthopanax sessiliflorus fruits;
Isolation;
Identification;
Chemical constituent
- From:
China Pharmacist
2016;19(3):460-463
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To isolate and identify the structures of triterpenoids from the extract of Acanthopanax sessiliflorus fruits. Methods:The chemical constituents were systematically isolated by column chromatography and liquid chromatography, and their struc-tures were determined by spectral data including 1 H-NMR, 13 C-NMR, HSQC and HMBC combined with ESI-MS. Results:Totally 8 trit-erpenoids compounds were isolated and identified from Acanthopanax sessiliflorus fruits, 22-α-hydroxychiisanogenin (1), chiisanogenin (2), 3-oxo-24-methylenecycloartan (3), mangiferonic acid (4), isomangiferolic acid (5), oleanolic acid (6), betulin (7) and betulin-ic acid (8). Conclusion:Compound 3, 4 and 5 are obtained from Acanthopanax genus for the first time.
