Effects of the Dachaihu decoction on intra-abdominal pressure in severe acute pancreatitis
10.3760/cma.j.issn.1673-4246.2016.02.005
- VernacularTitle:大柴胡汤对重症急性胰腺炎腹腔内压的影响
- Author:
Tao LI
;
Jun DUAN
;
Desheng CHEN
;
Shupeng WANG
;
Gang LI
- Publication Type:Journal Article
- Keywords:
Pancreatitis,acute necrotizing;
Da Chai Hu Tang;
Intra-abdominal pressure;
Intra-abdominal hypertension;
Abdominal compartment syndrome
- From:
International Journal of Traditional Chinese Medicine
2016;(2):110-113
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of the Dachaihu decoction on intra-abdominal pressure in severe acute pancreatitis. Methods 70 patients with SAP from China-Japan Friendship Hospital were randomly divided into two groups. 35 patients in a conventional treatment group were treated with conventional treatment of severe acute pancreatitis, and 35 patients in a Dachaihu decoction treatment group were treated with the decoction through nasogastric tube based on conventional treatment. The changes of intra-abdominal pressure and the morbidity of IAH and ACS in both groups were observed in acute stage. Results The intra-abdominal pressure in both groups increased. But the pressure in the Dachaihu decoction treatment group (13.31 ± 4.42 mmHg, 13.02 ± 5.23 mmHg, 12.35 ± 3.34 mmHg, 11.26 ± 4.46 mmHg, 9.89 ± 3.44 mmHg) was lower than the conventional treatment group (16.89 ± 5.71 mmHg, 17.52 ± 3.37 mmHg, 16.21 ± 2.15 mmHg, 14.57 ± 5.56 mmHg, 12.11 ± 1.28 mmHg) from the third day on (P<0.05). And the morbidity of intra-abdominal hypertension and abdominal compartment syndrome in the Dachaihu decoction treatment group were lower than the conventional treatment group in the whole acut stage (40%vs. 8.75%).The differences between two groups were statistically significant (P<0.05). Conclusion The Dachaihu decoction may significantly reduce the intra-abdominal pressure and the morbidity of intra-abdominal hypertension and abdominal compartment syndrome among patients with severe acute pancreatitis.
