Diagnosis of solitary pulmonary nodule by one-step spectral and perfusion imaging
10.3969/j.issn.1002-1671.2016.02.009
- VernacularTitle:一站式能谱及灌注成像鉴别诊断孤立性肺结节
- Author:
Suya WANG
;
Jianbo GAO
;
Pan LIANG
;
Huijuan XIAO
;
Ping HOU
;
Rui ZHANG
- Publication Type:Journal Article
- Keywords:
solitary pulmonary nodule;
spectral and perfusion imaging;
computed tomography
- From:
Journal of Practical Radiology
2016;(2):200-203
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of one-step spectral imaging and perfusion imaging in diagnosis of solitary pulmonary nodule(SPN).Methods Forty-seven patients with SPN proved by pathology underwent perfusion scan with gemstone spectral ima-ging mode,who were divided into malignant group in 28 patients and benign one in 1 9.The parameters of CT perfusion including blood volume (BV),blood flow (BF),mean transit time (MTT)and permeability surface (PS)were analyzed.Iodine concentration (IC),normalized iodine concentration (NIC)and slope rate of spectral curve in both arterial phase and venous phase were measured and calculated.The independent sample t test was performed to compare quantitative parameters between malignant and benign SPN.Results BF,BV and PS of malignant SPN were higher than those of benign ones (P <0.05).No statistically significantly differences between malignant and benign SPN were found (P >0.05).IC,NIC and slope rate of spectral curve in malignant SPN were higher than those in benign ones in both phases (P <0.05).Conclusion One-step spectral imaging and perfusion imaging can provide more parameters,which is helpful for the diagnosis of SPN.
