Quantifying the changes of endometrial microcirculation between pre-and postmenopause with MR DCE-PWI and IVIM-DWI
10.3969/j.issn.1002-1671.2016.02.017
- VernacularTitle:MR DCE-PWI 及 IVIM-DWI 定量绝经前后正常子宫内膜微循环改变
- Author:
Tianyou CHEN
;
Jinwei QIANG
;
Ruokun LI
;
Songqi CAI
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
dynamic contrast-enhanced;
intravoxel incoherent motion;
endometrium;
menopause
- From:
Journal of Practical Radiology
2016;(2):232-235
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the changes of endometrial microcirculation between pre-and postmenopause with magnetic resonance dynamic contrast-enhanced perfusion weighted imaging (MR DCE-PWI)and intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI).Methods Thirty-three patients with normal endometrium (premenopause in 21 and postmenopause in 12)confirmed by pathology underwent DCE-PWI,IVIM-DWI and conventional MRI.Quantitative parameters of DCE-PWI and IVIM-DWI in the endometrium were analyzed and compared between pre-and postmenopause groups.Results The DCE-PWI parameters were significantly higher in premenopause group than those in postmenopause one with significant differences in Ktrans (0.161±0.081)min-1 vs (0.097±0.054)min-1 , Kep (0.285±0.145)min-1 vs (0.184±0.119)min-1 and IAUC60 (20.854±10.695)mmol·kg-1 ·s vs (10.481±6.253)mmol·kg-1 ·s. No significant differences were found between the two groups in IVIM-DWI parameters including D,D* and f values.Conclusion DCE-PWI,rather than IVIM-DWI,can be used to quantitatively evaluate the changes of endometrial microcirculation between pre-and postmenopause.
