Clinical comparative research of tumor patient’s peripheral blood T-lymphocyte subset following CT guided percutaneous argon-helium cryoablation
10.3969/j.issn.1002-1671.2016.02.025
- VernacularTitle:氩氦刀对肿瘤患者外周血T细胞亚群影响的临床对照研究
- Author:
Guohong SHEN
;
Wei ZHANG
;
Wenlong ZHANG
;
Rui AN
;
Haixun LI
;
Hua HE
;
Lijun SUN
- Publication Type:Journal Article
- Keywords:
percutaneous argon-helium cryoablation;
hepatocellular carcinoma;
renal cell carcinoma;
peripheral blood T-lymphocyte subset
- From:
Journal of Practical Radiology
2016;(2):263-265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the response of tumor patient’s peripheral blood T-lymphocyte subset following CT guided per-cutaneous argon-helium cryoablation.Methods 122 patients with advanced of hepatocarcinoma or renal cell carcinoma undergone CT guided percutaneous argon-helium cryoablation.The percentage of peripheral blood CD3 + ,CD4 + ,CD8 + T-lymphocyte subset and the proportion of CD4 +/CD8 + T-lymphocyte were monitored at 2 h before and 20 h after the cryoablation respectively.Results The percentage of peripheral blood CD3+ ,CD4+ and CD3+ ,CD8+ T-lymphocyte were significantly increased after cryoablation,(measured by matched t-test,P<0.05).The ratio of CD4 +/CD8+ T-lymphocyte cells had an increase of 0.130(P =0.069).Conclusion The percentage of blood T-lymphocyte subset in patients with advanced hepatocellular carcinoma or renal cell carcinoma is increased significantly,when they are treated by using CT guided percutaneous cryoablation.The patient's tumor specific immunity is enhanced by CT guided percutaneous cryoablation.
