The Study of the diffusion tensor imaging in patients with primary trigeminal neuralgia caused by neurovascular compression
10.3969/j.issn.1006-5725.2016.06.012
- VernacularTitle:磁共振弥散张量成像在神经血管压迫关系所致原发性三叉神经痛中的应用
- Author:
Zhongxia LI
;
Zongfang LI
;
Zhenguang ZHANG
;
Jianqiang HUANG
;
Wei TIAN
- Publication Type:Journal Article
- Keywords:
Primary trigeminal neuralgia;
DTI;
FA;
ADC
- From:
The Journal of Practical Medicine
2016;32(6):907-910
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toexplore the application value of diffusion tensor imaging (DTI) in evaluating evaluation offunctional changes of the in patients with primary trigeminal neuralgia caused (PTN) by neurovascular compression. Methods 40 unilateral PTN patients and 40 healthy volunteers were enrolled in ourstudy.They allAll patients underwent the general sequences and DTI ,and then to measured the ADC and FA values of the trigeminal nerves. Results (1) Compared with contralateral side (0.408 ± 0.054)and bilateral sides in control group(0.423 ± 0.057), FA value of the ipsilateral side in PTN group(0.330 ± 0.056) was significant lower (P< 0.05)compared with the contralateral side (0.408 ± 0.054) and bilateral sides in control group (0.423 ± 0.057).The ADC value of ipsilateralside (2.052 ± 0.473)× 10-3 mm2/s was significantly higher (P < 0.05) thancompared withthe contralateral side (1.541 ± 0.266) ×10-3 mm2/s and bilateral sides in control group(1.431 ± 0.308) ×10-3 mm2/s. (2) An There's a nnegative correlation was found (r = -0.613,P < 0.001) between the loss of FA and the increase of ADC (r = -0.613,P < 0.001). Conclusion DTI could be used to evaluate the changes of neuratrophy and demyelination ,so it canmight be used of in diagnosis and treatment of PTNin further way.
