MRI characteristics and evaluation of cryptococcus meningoencephalitis in HIV-negative patients
10.3969/j.issn.1002-1671.2016.02.004
- VernacularTitle:HIV 阴性的隐球菌性脑膜脑炎的 MRI 表现及临床意义
- Author:
Tingyu YI
;
Wenhuo CHEN
;
Zongzhong WU
;
Yanmin WU
;
Yuehong CHEN
;
Meifang ZHANG
- Publication Type:Journal Article
- Keywords:
human immunodeficiency virus-negative;
cryptococcus meningoencephalitis;
magnetic resonance imaging;
prognosis
- From:
Journal of Practical Radiology
2016;(2):181-184
- CountryChina
- Language:Chinese
-
Abstract:
Objective To search MRI features of patients with HIV-negative cryptococcus meningoencephalitis (CM)and evaluate the value in judging the prognosis of CM.Methods The findings of cranial MRI and prognosis were retrospectively analyzed in 19 cases with India-ink capsule staining-proved HIV-negative CM in our department.The prognosis was evaluated by Glasgow Outcome Scale:score 1=death,score 2=persistent vegetative state,score 3=severe disability,score 4=moderate disability,score 5=good recovery. The patients with score 1-3 were classified as the group of poor prognosis,while those with score 4,5 as good prognosis.Results Abnormal manifestations on cranial MRI were observed in 84.2%(1 6/1 9)cases,meninges enhanced in 84.2% (1 6/1 9),brain edema in 31.6%(6/1 9),brain parenchyma lesion in 47.4% (9/1 9 ),vasculitis in 5.2% (1/1 9 ).The mean duration of follow-up was 3.5 years,The prognosis of 5/9(44.4%)cases with brain parenchyma lesion confirmed by cranial MR was poor.Conclusion The MRI manifestation of HIV-negative CM is diverse,and brain parenchyma lesion confirmed by cranial MRI may associated with poor prognosis.
