Spectral parameters analysis of pathologic differentiation of laryngeal and hypopharyngeal squamous cell carcinoma
10.3969/j.issn.1002-1671.2016.02.006
- VernacularTitle:不同病理级别喉及下咽鳞癌的能谱参数研究
- Author:
Liang YANG
;
Dehong LUO
;
Yanfeng ZHAO
;
Lin LI
;
Meng LIN
;
Chunwu ZHOU
- Publication Type:Journal Article
- Keywords:
squamous cell carcinoma;
computed tomography
- From:
Journal of Practical Radiology
2016;(2):188-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the discrepancy of parameters generated on dual-energy spectral CT (DECT)imaging in the different pathological grade of laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC),and to provide helpful information of the prognosis and the guide of clinical treatment.Methods 61 patients with pathologically confirmed LHSCC who underwent contrastenhanced DECT before therapy were retrospectively analyzed.The enhanced monochromatic data were analyzed with workstation.Iodine concentration of lesion (IC),water concentration of lesion (WC)and slope of spectral HU curve (s-SHC)were acquired.According to cell differentiation,all patients were divided into well,moderately and poorly differentiated groups.The difference of IC,WC,s-SHC,constituent ratio of T stage were compared among different groups.Results The IC and s-SHC had significant difference among well,moderately and poorly differentiated groups(F =3.56,3.96 respectively,P <0.05).The two-two paired comparisons demonstrated that there were significant difference of IC between poorly and well differentiated group(P <0.05).The others two-two paired comparisons demonstrated no significant difference (P>0.05).There were no significant difference of WC among three groups respectively (H =0.84,P >0.05).χ2 test showed that there was no significant difference for the constituent ratio of T stage among three groups (P >0.05).Conclusion IC and s-SHC can help to judge the pathological grade of LHSCC,and they may be useful to evaluate the prognosis of LHSCC.
