Value of CT perfusion imaging parameters for assessing the solitary pulmonary nodule-a Meta-analysis

VernacularTitle:CT 灌注成像参数评估孤立性肺结节的诊断价值--Meta 分析
Author: Weiwei SU ; Xiangsheng XIAO ; Jing LIU ; Xi LI ; Entao CAO ; Yuan FANG ; Hong YU
Publication Type:Journal Article
Keywords: solitary pulmonary nodule; computed tomography; blood volume
From: Journal of Practical Radiology 2016;(2):196-199
CountryChina
Language:Chinese
Abstract: Objective To evaluate the value of CT perfusion imaging (CTP)for solitary pulmonary nodule (SPN)by Meta-analysis.Methods Literatures about SPN diagnosed by CTP were filtered.PubMed,EMBASE,CNKI,VIP and WANFANG databases were searched for the relevant articles.The retrieved studies were screened according to the criteria for diagnostic research published by the cochrane methods group on screening and diagnosis.The quality of the articles was accessed and the basic data in the articles was extracted.Review Manager 5.3 software was used to compare the blood volume (BV)among different nodules,to perform heterogeneity test and analyze publication bias.Results A total of 1 7 studies with 877 lesions were included in the study.The random effect model was used for the existence of heterogeneity.The result showed the BV value of malignant SPN was higher than that of benign ones.Conclusion The result indicates that there exists significant difference in BV between malignant and benign SPN.The BV value,as one of the hemodynamic parameters of CTP,can be used as the diagnostic basis of SPN.