Characteristics of glucose tolerance in patients with nonalcoholic fatty liver disease and high blood pressure
10.3969/j.issn.1006-5725.2016.06.014
- VernacularTitle:伴有高血压的非酒精性脂肪肝患者的糖耐量特点分析
- Author:
Xuemei BAI
;
Ping LIANG
;
Jing ZHANG
- Publication Type:Journal Article
- Keywords:
Nonalcoholic fatty liver disease;
Hypertension;
Insulin;
Triglyceride
- From:
The Journal of Practical Medicine
2016;32(6):914-915
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate glucose metabolism , insulin secretion and serum lipid in patients of nonalcoholic fatty liver disease (NAFLD) with hypertension. Methods A total of 100 subjects including NAFLD with hypertension (n = 50) and NAFLD without hypertension (n = 50), in our hospital during Jul. 2010 to Jul. 2012, were enrolled in this study. Records the following information of the two groups: The clinical data , oral glucose tolerance and insulin releasing test , serum lipid , serum uric acid and ALT were recorded. Results Compared with the NAFLD without hypertension group, impaired glucose regulation was significantly increased in patients in the NAFLD with hypertension group(P < 0.05).The insulin releasing was significantly increased at 30 min and was increased at 180 min in patients in the NAFLD with hypertension group (P < 0.05).The insulin releasing during 30 min to 120 min was descend gradually in patients in the NAFLD with hypertension group,with no significant difference between these two groups. TG was markedly elevated in patients in the NAFLD with hypertension group (P < 0.05). Conclusion Prevalence of impaired glucose regulation was elevated obviously in NAFLD with hypertension group,and early-phase insulin secretion were reduced and delayed.
