Sister-Chromatid Exchanges in Lymphocytes of Medical Students Exposed to Formaldehyde.
- Author:
Soo Jin LEE
1
;
Jeong Il SON
;
Sang Hyo SIM
;
Kee Young KIM
;
Jaecheol SONG
;
Suo Ja CHU
;
Sung Han SHIM
;
Youl Hee CHO
;
Doo Jin PARK
Author Information
1. Department of Occupational medicine, Hanyang University Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Sister-chromatid exchange (SCE);
Formaldehyde;
Mutagenicity
- MeSH:
Formaldehyde*;
Humans;
Lymphocytes*;
Students, Medical*
- From:Korean Journal of Occupational and Environmental Medicine
1998;10(2):282-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sister-chromatic exchanges measured in the peripheral lymphocytes of 15 non-smoking medical students after exposure to formaldehyde during a 24-week anatomy class showed a small but significant (p=0.0468) increase when compared with samples obtained from the same individuals immediately before exposure. Mean frequencies of sister-chromatic exchange of cultured peripheral lymphocytes were 5.40+/-0.24 from the samples before exposure and 5.87+/-0.22 from the same samples after exposure. Breathing-zone air samples collected by formaldehyde monitoring kit with digital colorimeter (SKC) showed a mean concentration of 0.72+/-0.02 ppm formaldehyde.
